St. Catharines is the largest city in Canada's Niagara Region and the sixth largest urban area in Ontario, with 96.13 square kilometres (37.1 sq mi) of land and 133,113 residents in 2016. It lies in Southern Ontario, 51 kilometres (32 mi) south of Toronto across Lake Ontario, and is 19 kilometres (12 mi) inland from the international boundary with the United States along the Niagara River. It is the northern entrance of the Welland Canal. Residents of St. Catharines are known as St. Cathariners.
St. Catharines carries the official nickname "The Garden City" due to its 1,000 acres (4 km2) of parks, gardens and trails.
St. Catharines is located between the Greater Toronto and Hamilton Area (GTHA) and the Fort Erie – US border. Manufacturing is the city's dominant industry, as noted by the heraldic motto, "Industry and Liberality". General Motors of Canada, Ltd., the Canadian subsidiary of General Motors, was the city's largest employer, a distinction now held by the District School Board of Niagara. TRW Automotive operates a plant in the city, though in recent years employment there has shifted from heavy industry and manufacturing to services.