The Keurbooms River is a river in the Western Cape Province in South Africa. The river has its sources south of Uniondale in the Langkloof and flows in a roughly southeastern direction. It passes De Vlugt and the Prince Alfred Pass, flowing along the northern side of the R340 road then it turns south. After crossing the N2 road, it flows into the Indian Ocean through the Keurbooms Estuary, located close to the coastal town of Plettenberg Bay.
The Keurbooms River is approximately 85 km long with a catchment area of 1,080 km2. Its main tributary is the Bitou (Bietou).