Buffalo is a city in western New York state and the county seat of Erie County, on the eastern shores of Lake Erie at the head of the Niagara River. As of 2016, Buffalo is New York state's second most populous city after New York City, with 275,983 residents. The metropolitan area has a population of 1.13 million, while the larger, cross-border Buffalo Niagara Region includes 8 US counties and 2 Canadian municipalities and has a population of 2,493,869.
Buffalo grew significantly in the 19th and 20th centuries as a result of the Erie Canal, railroads and Lake Erie, providing an abundance of fresh water and an ample trade route to the midwestern United States, while grooming its economy for the grain, steel and automobile industries during the 20th century. After an economic downturn in the latter half of the 20th century, Buffalo's economy has transitioned to sectors that include financial services, technology, biomedical engineering and education.
Buffalo is known as "The Queen City", "The Nickel City" and "The City of Good Neighbors". Its residents are called Buffalonians.